Wednesday, June 20, 2012

Beyond Illness

The accumulation of fat in the abdominal region is classified as the type of obesidade that offers to greater risk for the health of the population. This excess of weight centered in the abdominal region, is called of obesidade android, and can be measured by the abdominal circumference, following the parameter of measures > 80 cmpara the women and > 94 cmpara men. This parameter is a way of if evaluating the individual for the risk to the illnesses, as the cerebral cardiovascular illness. According to Bergmann (2010), people with raised values of abdominal circumference more, possess a bigger risk to present, cardiovascular illness cerebral in comparison to those with values normais.5 In the obesidade, the fabric adiposo becomes inflamed due the production of inflammatory citocinas for the adiposas cells and the infiltration of macrophages, this inflammation of the fabric adiposo is a stage in the development of the resistance insulina.6 the inflammatory state occurs due to resistance to the insulina and other clutters associates to the obesidade, as hiperlipidemia and metabolic syndrome. One gives credit that the inflammation is a consequncia of the obesidade. However, it tells Of them that the obesidade is in fact the result of an illness inflamatria.7 enzyme 11 hidroxiesteroide beta desidrogenase (11BHSD-1), that it has the function to convert corticosterona into cortisol can be the cause for the increase of the obesidade visceral.8 It involved one in the increase of the abdominal circumference also estresse this, generating stimulaton of the secretion of cortisol for the hiperativao of the hipotlamo-hipfise-adrenal axle (HHA) that as defense form liberates catecolaminas and cortisol. Healthy Living spoke with conviction. The neurons of paraventricular of hipotlamo (PVN) synthecize the liberating hormone of corticotrofina that is set free in hipfise previous to stimulate the production and corticotrofina secretion, that in turn will stimulate the adrenal cortex to produce and to secretar cortisol.9 the hiperativao of axle HHA, leads to an extreme production of cortisol, and cortisol is associated with many metabolic events that they stimulate I accumulate it of fat visceral.6 Beyond the activation of axle HHA, the increase of cortisol also increases the activity of the enzyme 11BHSD-1 in visceral fabrics, that corticosterona passes converting circulating into cortisol.

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